Scientists have coped with impaired motor skills in mice with Parkinson's disease
Parkinson's disease is extremely unpleasant, well-studied and still incurable disease. And recently, a research team, University of Helsinki, led by Dr. Timo Mohanena able to make a discovery, thanks to which, though not able to fully cope with the disease, but managed to overcome the disturbances in motor function of Parkinson's disease. This could be a real breakthrough in the treatment of this disease.
As a general rule, the existence of Parkinson's disease, a person learns at the stage when the manifest violations of motor function. According to WHO, of parkinsonism in the world affects about 2% of people over the age of 60 years. The disease destroys nerve cells in the brain areas that are responsible for motor function. The exact cause of the disease is still not clear, but recent studies have focused on the protein alpha-synuclein, which is including also responsible for motor function. This protein can form a cluster, and if the patient is suffering from Parkinson's disease - these clusters are collected within its nerve cells, damaging them. Additionally, alpha-synuclein can propagate from one cell to another like infection. Based on recent studies, the formation of abnormal protein aggregates is regulated by an enzyme PREP. And on it and concentrated scientists. During the experiments, the researchers selected a group of rodents with excessive production of the protein alpha-synuclein. Making sure that the mice began to show simtomy Parkinsonism, specialists began therapy with lock PREP. As a result, two weeks later the symptoms virtually disappeared after the end of the experiment did not return. Analysis of the blood of rodents showed that blocker PREP protect the brain regions responsible for motor skills, damage, and "removed" from the affected brain cells abnormal protein accumulation.