In the US there was the most expensive medicine
• In the US, there was a very expensive medicine
It goes on sale the most expensive in the history of US medicine - the cost of 850 thousand dollars (48 million rubles) for packaging. Remember this name: Luxturna. From now on it is the most expensive drug in the world. His early this year will release Philadelphia based pharmaceutical company Spark Therapeutics, which specializes in gene therapy.
In December 2017 the US Office of Food and Drug Administration (FDA) approved Luxturna gene therapy for the treatment of a rare hereditary retinal disease - Leber's congenital amaurosis. Developed by US company Spark Therapeutics, Luxturna the first gene therapy, which with the help of a genetically modified virus fixes directly in the patient's genome cells of the retina, providing a partial restoration of vision.
RPE65 gene encodes the production necessary for normal vision and the enzyme responsible for the formation of light the eye receptors, but if a man will get his copy of the defective, it will cause Leber's congenital amaurosis and retinitis pigmentosa. Both diseases are expressed in the deterioration of vision and the risk of blindness. Salvation could be gene therapy.
Luxturna is a solution with a genetically modified virus carrying a "correct" gene PRE65. The virus is injected directly into the eyeball and starts production in the retina corrected enzyme. The operation lasts only 45 minutes. It reported that enough single use drug. The package will contain two doses - one in each eye (ie, 425 thousand dollars per dose). Testing has proven that Luxturna really restores sight to those who has a rare form of inherited blindness. It is estimated that in the United States with this diagnosis forced to live nearly two thousand people.
Spark Therapeutics originally going to release the drug into the market at a price of one million dollars, but the insurance companies have convinced it to reduce some of this amount. In America, the majority of drugs, prescription by prescription, at least partially paid for insuring the health of companies.
And though it is a colossal price for the drug, Luxturna - a real breakthrough in medicine because gene therapy can help in the fight both with hereditary diseases and cancer, most cases that begin with DNA damage.
To date, the most expensive medicine in the world has been used in Europe but not the United States who had a license drug Glybera gene therapy from the company uniQure. Its cost was 1, $ 2 million. However, in his last year laid off due to lack of demand. This medicine is intended for gene therapy of a rare hereditary disease - lipoproteinazy enzyme deficiency.